PEPFAR, the Presidents Emergency Plan for AIDS Relief, was launched in 2003 by President George W. Bush.
PEPFAR supports HIV prevention, testing and antiretroviral treatment, as well as prevention of mother-to-child transmission, care for orphans and vulnerable children, tuberculosis services for people with HIV and broader health-system strengthening. The program initially focused on emergency treatment and prevention, later shifting toward partnership frameworks with recipient governments, epidemic control targets and long-term sustainability. By September 2025, PEPFAR was credited with saving more than 26 million lives and preventing 7.8 million infants from acquiring HIV at birth. But PEPFAR is under attack.
The second Trump administration has devastated PEPFAR by dismantling USAID in April 2025.
Read more about PEPFAR in two news articles.
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